Tuesday, 4 October 2011
renal physiology
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Suppose a person loses the function of half his nephrons because of renal degenerative disease. Assuming the person survives and reaches a new steady state and that body urea production remains normal, which of the following would be expected to decrease below normal?
A. plasma urea concentration
B. renal urea excretion
C. renal urea clearance
D. urine urea concentration
E. all of the above
C. Less urea would be cleared because less urea is be filtered. The reduced filtration would cause blood urea concentration to rise until the amount of urea excreted was equal to the amount of urea produced by protein metabolism even with the reduced plasma clearance.
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